• ReYOUvenation - The Science of a Better You

    Innovative anti-ageing Stem Cell treatment for your skin, brain & body. 

  • Stem Cell Anti-Aging Treatment

    Learn about the latest Stem Cell 2.0 therapy

    designed for you, from your own stem cells.

  • Anova IRM - The Science of a Younger You

    “Ever since we invented fire and the wheel, we've been demonstrating both our

    ability and inherent desire to fix things that we don't like about ourselves“

    - Aubrey de Grey

Why We Age

Aging is a complex biological process in which cells become progressively damaged over time and eventually die. As we age, fewer and fewer cells are replaced, slowly wearing out our bodies. This means that over time the damage accumulated in our bodies will become so immense, that at one point the body will not be able to cope with it - ultimately leading to our death.

Environmental factors such as: exposure to sun - "solar radiation", injuries, smoking, air and water pollution, etc., and genetics contribute to speeding up the process of aging as well.
Aging affects our skin negatively by disturbing the normal function of skin cells. A majority of diseases are a result of aging. Our skin cells experience enourmous amount of damage on a daily basis. They are exposed to constant bombardment of tens of thousands harmful elements each day, causing irregular pigmentation (skin discoloration or hyperpigmentation) and loss of elasticity in skin.

Aging is involved in many other processes that such as accumulation of senescent cells, oxidative stress, immune and hormonal system changes. All of these factors contribute to increasing the risk of cancerous diseases.

Effects of Anova's reYOUvenation on Anti-Aging

Stem cells are the solution of the future. Forget about your expensive beauty creams and cosmetics as they do not attack aging on the right level. They promise only temporary or superficial solutions to your aging problems. Most of them function by masking the processes of aging on the surface level, but never offer solid solutions to where aging really happens.

Latest research in regenerative science provides concrete proofs that aging actually takes place at the cellular level. This is where aging needs to be stopped!

Are you looking for long lasting solution to aging?
Then give us a call!


Anova offers the best and latest stem cell-based therapies for anti-aging. Our therapies are potentially capable of repairing the effects of aging - effectively extending your life. They act on the cellular level, by optimizing and revitalizing the functions of your whole body, not just the surface. Our specialists make use of your own stem cells to rejuvenate you and make you feel young and powerful again!

We are the Science of a Younger You!

All stem cell-based procedures at Anova are personalized and are in full accordance with the strict quality standards of Germany and the respective healthcare regulations.

To find out what treatment is best suited for you, our highly trained specialists will subject you to a detailed full-body examination, before deciding on the specifics of the prospective anti-aging treatment.

The medical diagnostics team at Anova will help you obtain a general idea of your body’s current health status by performing:

          * In-depth medical history
          * General physical exam
          * Personalized clinical chemistry
             (blood and urine)
          * Cardio-vascular evaluation including
             (EKG, Echocardiography, Cardio-CT, MRI, etc.)
          * Cancer check with tumor markers
          * Whole-body MRI
          * Virtual colonoscopy
          * Low-dose CT of the lungs (smoker)
          * MR-mammography, etc.

Additional anti-aging treatments may include:

          * Metabolic and body composition optimization
          * Hormone optimization
          * Antioxidation treatment
          * Dietary optimization
          * Personalized exercise program

AntiAgingTable
References and Literature - Stem Cell-based Therapies and Anti-Aging (Click for more)

Park, Byung-Soon, and Won-Serk Kim. "Adipose-Derived Stem Cells and Their Secretory Factors for Skin Aging and Hair Loss." Textbook of Aging Skin (2017): 205-224.

Xu, Dan, and Hidetoshi Tahara. "The role of exosomes and microRNAs in senescence and aging." Advanced drug delivery reviews 65.3 (2013): 368-375.

Prattichizzo, Francesco, et al. "Exosome-based immunomodulation during aging: a nano-perspective on inflamm-aging." Mechanisms of Ageing and Development (2017).

Basu, Joydeep, and John W. Ludlow. "Exosomes for repair, regeneration and rejuvenation." Expert opinion on biological therapy 16.4 (2016): 489-506.

Park, Byung-Soon, and Won-Serk Kim. "Adipose-derived stem cells and their secretory factors for skin aging." Textbook of Aging Skin. Springer Berlin Heidelberg, 2010. 201-212.

Soto-Gamez, A., & Demaria, M. (2017). Therapeutic interventions for aging: the case of cellular senescence. Drug Discovery Today.

Moiseeva, O. et al. (2013) Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-kB activation. Aging Cell 12, 489–498.

Martin-Montalvo, A. et al. (2013) Metformin improves healthspan and lifespan in mice. Nat. Commun. 4, 2192.

Pitozzi, V. et al. (2013) Chronic resveratrol treatment ameliorates cell adhesion and mitigates the inflammatory phenotype in senescent human fibroblasts. J. Gerontol. A Biol. Sci. Med. Sci. 68, 371–381.

Lim, H. et al. (2015) Effects of flavonoids on senescence-associated secretory phenotype formation from bleomycin-induced senescence in BJ fibroblasts. Biochem. Pharmacol. 96, 337–348.

Toso, A. et al. (2015) Enhancing chemotherapy efficacy by reprogramming the senescence-associated secretory phenotype of prostate tumors: a way to reactivate the antitumor immunity. Oncoimmunology 4, e994380.

Xu, M. et al. (2015) Targeting senescent cells enhances adipogenesis and metabolic function in old age. eLife 4, e12997.

Liou, C.J. et al. (2014) Oral lovastatin attenuates airway inflammation and mucus secretion in ovalbumin-induced murine model of asthma. Allergy Asthma Immunol. Res. 6, 548–557.

Mian, B.M. et al. (2003) Fully human anti-interleukin 8 antibody inhibits tumor growth in orthotopic bladder cancer xenografts via down-regulation of matrix metalloproteases and nuclear factor-kappaB. Clin. Cancer Res. 9, 3167–3175.

Karkera, J. et al. (2011) The anti-interleukin-6 antibody siltuximab down-regulates genes implicated in tumorigenesis in prostate cancer patients from a Phase I study. Prostate 71, 1455–1465.

Pellegrini, G. et al. (2004) Telomerase activity is sufficient to bypass replicative senescence in human limbal and conjunctival but not corneal keratinocytes. Eur. J. Cell Biol. 83, 691–700.

Abad, M. et al. (2013) Reprogramming in vivo produces teratomas and iPS cells with totipotency features. Nature 502, 340–345.

Sagiv, A. et al. (2013) Granule exocytosis mediates immune surveillance of senescent cells. Oncogene 32, 1971–1977.

Demaria, M. et al. (2014) An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA. Dev. Cell 31, 722–733.

Pei, Ming. "Environmental preconditioning rejuvenates adult stem cells' proliferation and chondrogenic potential." Biomaterials (2016).

Vañó-Galván, S., and F. Camacho. "New Treatments for Hair Loss." Actas Dermo-Sifiliográficas (English Edition) (2017).

Anitua, Eduardo, Ander Pino, and Gorka Orive. "Opening new horizons in regenerative dermatology using platelet‐based autologous therapies." International journal of dermatology 56.3 (2017): 247-251.

Patient Services at Anova IRM Stem Cell Center

Located in the Center of Germany

Less than 20 minutes from Frankfurt Airport

Personalized Therapies for Your Improvement with State-of-the-art Stem Cell products and latest Regenerative Medical Programs

100% Guarantee on Cutting-edge, safe and high quality stem cell products with 20-times increased cell counts

Highest Precision with Latest Radiological Imaging Modalities for Superior Image Guided Procedures

Diagnostic Work-ups with World-Class MRI scans, Advanced Blood Analysis programs and Check-up

Personal Service with Friendly, Dedicated Professional Patient Care Managers

Scientific Collaborations with Renowned Academic Institutions

Scientific Data Acquisition and Publishing

Travel Visa and Concierge Service

Contact us:

Strahlenberger Straße 110
63067 Offenbach am Main

Tel.: +49 (69) 50 50 00 944

Or let us call you back within 24h

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