Stem Cell treatment for Osteoarthritis (OA):

Treat the Disease, Not the Symptoms

Stem Cell treatment for Osteoarthritis (OA): Treat the Disease, Not the Symptoms

Osteoarthritis is a leading cause of pain and disability across the world. With the population getting older and the desire for individual freedom (at older age) is increasing, new therapeutic approaches are urgently needed.

Current therapies are mainly targeting the symptoms, however, none are able to structurally modify the processes of OA or prevent the disease's progression. Stem cell therapies have yieled impressive results in regenerating damaged tissues, and partly reverting the underlying aging and immunologically-related processes of osteoarthritis.

With the next generation of stem cell-based therapies, the Anova Stem Cell Secretome therapy, in combination with conventional (stem cell-based) methods like BMC and PRP, we are offering an entirely new regenerative approach to treating Osteoarthritis.

Recent evidence-based scientific research has shown that stem cell-based therapies are able to effectively modulate the immune responses of OA, regenerate lost nerve supply, differentiate into chondrocytes (the cells that produce cartilage), etc., and offer long lasting effects for treating OA, as compared to standard medications (like Nonsteroidal Antiinflammatory Drugs 'NSAIDs') that temporarily mask the symptoms only.

For more information about our stem cell-based treatments and how interact with Osteoarthritis, please feel free to contact us. We are always here for you.

Frequently Asked Questions: Stem Cell treatments
and Regenerative Therapies for Osteoarthritis

What causes Osteoarthritis?

Osteoarthritis grafik

Osteoarthritis is mainly considered a cause of aging, where aging itself is a complicated process which is not entirely understood. Younger people sometimes get early osteoarthritis, primarily in the form of joint injuries or excessive strain.

Risk factors are:

  • Joint injury
  • Joints that are deformed
  • Genetic defects related to joint cartilage
  • Stress on the joints from certain jobs or sports
  • Being overweight
  • Getting older

What other treatments for Osteoarthritis are there?

Doctors often combine treatments that are optimized to fit a patient's needs, lifestyle, and health. Osteoarthritis treatment has four main goals:

  • Control of the pain
  • Improve joint function
  • Keep a healthy body weight
  • Achieve a healthy lifestyle

Osteoarthritis treatment plans can involve:

  • Exercise
  • Weight control and diet, such as:
    • Low staturated fat, high fiber-rich, fruits and vegetables. Some nutrition supplements appear to be helpful.
  • Rest and joint care
  • Nondrug pain relief techniques to control pain
  • Medicines
  • Complementary and alternative therapies

What is Bone Marrow Concentrate (BMC)?

Bone Marrow concentrate (BMC) is a source for Mesenchymal Stem Cells (MSCs). It contains many important growth and regenerative factors, in addition to the Mesenchymal Stem Cells. The procedure is relatively simple and minimally invasive, therefore it has been a favourite source for stem cell-based therapies in the previous decades. Many groups rely on BMC as their main stem cell treatment, sometimes with exaggerated claims. However, BMC has demonstrated impressive results for effective treatment of numerous diseases, among them being osteoarthritis.

For additional information you may read our page about BMC or contact us if you are interested in getting a BMC treatment.

What is Platelet Rich Plasma (PRP)?

Platelet Rich Plasma (PRP) is a blood-derived, cellular product with concentrated supply of regenerative growth factors and cytokines, obtained from the the patient's own blood. It is very simple to acquire, and it has shown promising results in the treatment of several inflammatory and degenerative diseases. For the treatment of specificic diseases, it can be combined with BMC or adMSCs as it has synergistic additive effects to the treatment. PRP has "special" functions, such as: it serves as a growth medium to maintain stem cells healthy; ensures adequate cellular environment where enough energy is provided to allow the cells to perform their regenerative work, when injected.

For additional information read our page about PRP, or contact us for more information.

What is Regenexx Stem Cell and PRP procedure, and why is Anova using a different approach?

Regenexx is a US based professional group with many years of experience in BMC and PRP treatments. In contrast to other groups, they work with medical professionals and gather data that is also partly published in peer reviewed journals.

Limited to BMC and PRP they expand to clinics outside, for more extensive stem cell therapies.

However, Anova, instead of going into unregulated countries, has designed the next generation of stem cell treatment in full communication and regulatory compliance in the centre of Europe. Offering a much more effective, safe and repetitive treatment that is optimized for best effects; and not on "hoping for the best", by simply injecting stem cells to treat patients.

References and Literature - Stem Cell-based Therapies and Osteoarthritis (Click for more)

MSC, BMC, Stem Cell Secretome and EVs

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PRP

Rubio-Azpeitia E, Andia I. Partnership between platelet-rich plasma and mesenchymal stem cells: in vitro experience. Muscles Ligaments Tendons J. 2014;4(1):52–62.

Others

Xu, Ming, et al. "Transplanted senescent cells induce an osteoarthritis-like condition in mice." The Journals of Gerontology Series A: Biological Sciences and Medical Sciences (2016): glw154.

McCulloch, Kendal, Gary J. Litherland, and Taranjit Singh Rai. "Cellular senescence in osteoarthritis pathology." Aging Cell (2017).

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